Detailed Introduction:

The method for synthesizing o-amino-p-tert-butylphenol through nitration of p-tert-butylphenol involves catalytic hydrogenation reaction in a high-pressure reactor using o-nitro-p-tert-butylphenol as raw material, methanol as solvent, and Raney nickel as catalyst; The mass ratio of o-nitro para tert butylphenol to methanol (m/v) is 1: (10-12), the mass ratio of catalyst to o-nitro para tert butylphenol is 1: (20-30), the reaction pressure is 0.4-0.6 Mpa, the reaction temperature is 30-40 ℃, and the reaction time is 6-8 hours; The system is cooled to 20-30 ℃ and subjected to pressure filtration, concentration, crystallization, centrifugation, and drying under inert gas protection to obtain a white powdered o-amino-tert-butylphenol. It can react under lower temperature and pressure conditions to obtain ortho amino para tert butyl phenol with higher purity and yield. It has the advantages of less oxidation in the production process to ensure product color, less wastewater, reusable solvent methanol, low pollution, and controllability.